STRUCTURAL CHARACTERIZATION OF A RECOMBINANT FUSION PROTEIN BY INSTRUMENTAL ANALYSIS AND MOLECULAR MODELING.


Tumor immune microenvironmental characteristics in Human Epidermal Growth Factor-2 (HER2) positive esophageal adenocarcinoma: A comparative analysis and biomarker study

Background: HER2 targeting in esophageal adenocarcinoma (EAC) has shown potential, but often fails to show durable response.Given the contributions of the tumor immune microenvironment (TIME) to therapeutic responses, we aimed to chart the TIME characteristics of HER2 positive tumors.Methods: 84 biopsies were taken from the TRAP cohort (neoadjuvant

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